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Liver Disease: Causes, Risk Factors, Symptoms, Prevention & Treatment

  • Liver Disease Causes

Infection: Various infections can cause liver disease, the most common types of liver infection are hepatitis viruses such as Hepatitis A, B, C & E

Liver Disease

Chronic Alcohol Abuse: Most common cause of liver cancer and indication for liver transplant
Fatty Liver: Common causes of fatty liver are obesity, hypertriglyceridemia, diabetes
Immune system abnormality: Examples include Autoimmune hepatitis, Primary sclerosing cholangitis, Primary biliary cirrhosis
Other Causes: Drugs and Toxins, Genetics

  • Risk Factors: Following factors may increase your risk for Liver problem

  • Alcohol Abuse
    Diabetes
    Obesity
    Exposure to certain toxins or chemicals
    Unprotected sex
    Injecting drugs using shared needles
    Blood transfusion
  • Liver Disease Symptoms

  • Yellowish discoloration of skin and eyes (Jaundice)
    Nausea & Vomitting
    Chronic Fatigue
    Pruritus / Itching
    Abdomen pain and distension (Ascites)
    Swelling or edema in the ankle and leg
    Dark colored urine
    Pale stools
    Loss of appetite
    Blood in the vomitus (Hematemesis)
    Fresh blood in the stool (Hematochezia) or Black tarry stools (melena)
  • Liver Disease Treatment

Treatment varies from life-style modifications to drugs to surgery depending on the specific cause. Changes in life-style include stopping alcohol use, regular exercise, diabetes and weight control for fatty liver, Chronic liver damage is managed conservatively with drugs initially and Liver transplant for end stage liver problem

  • Liver Disease Prevention

Healthy life style with regular exercise and weight management is must for healthy liver. Diabetes control. It is predicted that Fatty liver will be the leading cause of liver failure  and liver cancer in future. Avoid alcohol intake and smoking. Hepatitis B vaccine is available. Unprotected sex, infected blood transfusion, sharing infected needles are risk for hepatitis infection and should be avoided

Dr Amit Jain MS MCh (GI Surgery) is Best GI Surgeon in Delhi for Liver Disease. Call us at 7351088686 for your queries. Visit our facebook page Dr Amit Jain Laparoscopic Gastrointestinal Cancer & Bariatric Surgeon to know more about Liver problems

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Liver Cancer Treatment

Liver Cancer Treatment
Liver Cancer Treatment

Liver Cancer Treatment depends whether liver cancer develops under the background of normal or diseased liver. Chronic liver disease is risk factor for liver cancer. The main cause of chronic liver disease is alcohol intake, Hepatitis B & C infection, Fatty liver disease. These patients have a very high recurrence rate after liver resection and liver transplant is preferred in these patients if donor is available. Various local ablative procedures are available if patient is not fit for surgery or as palliative treatment for advance cancer

  • Liver Resection as Liver Cancer Treatment

Liver resection is first line of treatment if cancer occur in normal liver and after resection adequate amount of liver volume can be saved for normal liver function. It is said that about 30% of normal liver volume should be left after resection for adequate liver function

  • Liver Transplant as Liver Cancer Treatment

In patients of chronic liver disease who develop liver cancer, transplant is preferred if fulfills the criteria for transplant and donor is available. If there is long waiting list for donor meanwhile liver resection or local ablative procedure can be done
Milan criteria for liver transplant in liver cancer patients is associated with 70% 5 year survival rate. These criteria include a single tumor wth size 5 cm or less, maximum three tumors with size 3 cm or less and without evidence of vascular invasion. If tranplant is done beyond these criteria long term survival rate may not be good

  • Local Ablative Procedures as Liver Cancer Treatment

Ablation means tissue destruction without removing them. This technique is used in liver cancer when there are few small tumors and surgery is not a good option because of poor liver function/ poor health status of patient/ long waiting list for liver transplant. Various ablative procedures available are Radiofrequency ablation (RFA), Microwave ablation (MWA), Cryoablation (Cryotherapy), Ethanol (Alcohol) ablation

Consult Dr Amit Jain Best Oncosurgeon in Delhi Noida Ghaziabad NCR India for Liver Cancer. Call us at 7351088686 for your queries

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Surgical Obstructive Jaundice: Causes & Treatment

What is Surgical Obstructive Jaundice

Obstruction of the bile flow into the duodenum lead to accumultion of bile pigments.As the cause of jaundice is obstruction it is called as obstructive jaundice and as it require surgical intervention it is called as surgical obstructive jaundice

Clinical Features of Surgical Obstructive Jaundice

The most prominent clinical feature which distinguish medical jaundice from surgical jaundice is pale stool in surgical jaundice. Because of obstruction bile pigments does not reach up to intestine and stools become pale. Patient complain of itching due to accumulation of bile salts in the blood

Surgical Obstructive Jaundice
Surgical Obstructive Jaundice
Liver Function Tests in Surgical Obstructive Jaundice

Total bilirubin level is raised. It is conjugated type of bilirubin which is raised in obstructive jaudice. Serum alkaline phosphatase level is raised, it indicates there is obstruction in bile passage

Radiology

Ultrasound is the first investigation to be done as it is non-invasive, no radiation exposure and readily available. Dilatation of Biliary radicles is indicative of obstructive biliopathy. Level of biliary tract dilatation is suggestive of site of obstruction. The most common cause of surgical obstructive jaundice is Common Bile duct stones. In old age patients malignancy can be the cause of  jaundice. Small CBD stones may be missed on Ultrasound.
MRI/MRCP to detect small CBD stones missed on ultrasound. Biliary anatomy is more defined on MRI.

Treatment

Vitamin K is administered to correct coagulation profile before any intervention. If patient is in cholangitis proper antibiotic and I.V fluids are administered. Specific treatment depends on the cause of CBD obstruction. The first line of treatment for CBD stones is ERCP stone clearance. Surgery is done for malignant cause of jaundice.

Consult Dr Amit Jain Best Gastrosurgeon in Delhi Noida Ghaziabad for Management of Surgical obstructive jaundice. Dr Amit Jain is renowned Gastrosurgeon in East Delhi specialized in Laparoscopic GI Surgery.Call us at 7351088686

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