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Gastrointestinal Cancer: An Overview

Gastrointestinal CancerThe incidence of gastrointestinal cancer is increasing. Reason being change in lifestyle, dietary habits, increased alcohol intake and smoking.The prognosis of gastrointestinal cancer patients is good if it is detected early and treated at early stage.Anorexia and weight loss are common symptom in cancer patients, along these symptoms with some GI symptoms if present should not be ignored and doctor should be consulted. There are various screening programmes for early detection of colo-rectal and liver cancer. These programmes are done for high risk patients. Screening Colonoscopy is done for patients with inflammatory bowel disease, family history of colo-rectal cancer diagnosed at early age. Regular ultrasound is done in chronic liver disease patients. Neo-adjuvant therapy for locally advance cancer of esophagus, rectum and pancreas has shown good result. Pre-operative biliary drainage is done in patients with high bilirubin who require liver resection

  • Upper Gastrointestinal Cancer

It include cancer of the esophagus, stomach, duodenum and small intestine.Dysphagia, Vomitting,melena are common symptom. Upper GI Endoscopy is helpful for diagnosis. CECT chest and abdomen for staging.

  • Lower Gastrointestinal Cancer

Cancer of the colon and rectum are lower gastrointestinal cancer. Most common symaptoms are altered bowel habits, blood in stool. Diagnosis is made by Colonoscopy. CECT abdomen for staging.MRI is done for cancer rectum There is role of Neoadjuvant therapy in locally advance rectal cancer.Surgery is the treatment of choice if cancer is resectable

  • Hepato-Biliary GI Cancer

It include cancer of the liver, gallbladder, bile duct and pancreas. Patient have symptom of right sided pain abdomen with jaundice. CECT abdomen along with MRCP is helpful to delineate biliary anatomy

  • Symptoms of GI Cancer

Vomitting

It occur when there is obstruction in the gastrointestinal tract. Obstruction distal to the bile duct opening causes billious vomitting. Obstruction proximal to it causes non-billious vomitting.Primary stomach cancer or small bowel cancer casues vomitting due to intrinsic mass which compromise the lumen. Gallbladder mass can cause external compression over the duodenum and antro-pyloric region resulting in gastric outlet obstruction

Dysphagia

Early and Common symptom of esophagus cancer. In patients with esophagus cancer patients have initial dysphagia to solid foods and gradually progress to liquid. This progressive dysphagia is indicative of any progressive mass lesion in the esophagus which is compomising the esophagus lumen and causing dysphagia

Jaundice

It occur when there is obstruction in the Common bile duct. Most common symptom of hepato-biliary gastrointestinal cancer symptom.This obstruction can be intrinsic due to bile duct cancer. It may be extrinsic due to external compression such as Gallbladder mass or pancreatic head mass causing external compression over the CBD. patient present with features of obstructive jaundice such as pale colored stool, dark urine and pruritus

It is passage of black tarrish colored stool. Melena indicate slow bleed in the GI tract. This bleed can originate at any site along the GI tract. Cancer stomach and peri-ampullary cancer and right sided colon cancer have a tendency to bleed. Sometimes patient have occult bleed and present with feature of anemia such as weakness/tiredness

Hematochezia

It is the passage of fresh blood per rectum. symptom of lower gastrointestinal tract cancer that is colo-rectal cancer

Anorexia and Weight Loss

These are common symptoms of any malignancy in our body

Dr Amit Jain MS MCh (GI Surgery) is Best Gastro Doctor in Delhi Noida Ghaziabad Indrapuram. Call us at 7351088686 for your queries. 

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Gallbladder Cancer Risk Factors: Are You

All Cancers have some risk factors. Some can be changed such as alcohol,obesity and smoking. Some cannot be changed like family history and age. Most of the gallbladder cancer risk factors are non-modifiable. Having a risk factor does not indicate that definitely patient will get cancer and few patients develop cancer without any risk factor
But definetly presence of risk factors increases the chances of getting cancer. Various gallbladder cancer risk factors have been identified

  • Gallstones: Common Among various Gallbladder Cancer Risk Factors

Among many gallbladder cancer risk factors one is gallbladder stones. More than 70% of patients with gallbladder cancer have gallstones when they’re diagnosed.The incidence of gallbladder cancer is rare as compared to gallstones as most patients with gallbladder stones will never have gallbladder cancer

  • Porcelain gallbladder

It is a condition where gallbladder wall is covered with deposits of calcium.Can occur after chronic cholecystitis or long term inflammation of the gallbladder

  • Female gender

The incidence of gallbladder cancer is more in females as compared to men.It may be correlated with increased incidence of gallstones and inflammation in the gallbladder in females

Gallbladder Cancer Risk Factors
Gallbladder Cancer Risk Factors

Obesity

It has been found that gallbladder cancer patients are obese or overweight. Gallstones are also more common in obese patients which may also explain the high risk for gallbladder cancer in these patients

  • Older age

As most cancer develop in old age same with gallbladder cancer.But incidence is increasing in young population also. In this age group it has been found that gallbladder cancer is more aggressive. Reason may be dietary and life style change

  • Ethnicity and geography

Worldwide, Incidence of gallbladder cancer is more in Central America, Pakistan and India. In India it is more common in North as compared to south

  • Choledochal cyst

These are cystic dilatation of biliary channels which are congenital

  • Gallbladder polyps

The incidence of Gallbladder cancer is more in gallbladder polyps which are more than 1cm in size, single polyp and sessile

Dr Amit Jain MCh Best Oncosurgeon in Noida

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Gallstone: Causes, Diagnosis & Treatment

Gallstone disease is common and its incidence is more in female. The Treatment of choice for gallstone is surgery. The Standard Gallbladder Operation is called Laparoscopic Cholecystectomy in which whole of the gallbladder is removed. As mostly it is done laparoscopically it is called as laparoscopic cholecystectomy. There is no role of medications in the treatment of Gallbladder stones. The rate of complications due to gallstones does not depend on the number and size of stones

  • What causes Gallstones

There are various theories regarding the formation of Gallstone. There is no definitive preventive method.

  • Gallstone Diagnosis

The mainstay of gallstone diagnosis is Ultrasound Abdomen. It will detect the number and size of gallstones. Any associated stones in the Common Bile Duct. Thickening in the gallbladder wall. If there is any doubt of gallbladder cancer on ultrasound CECT abdomen should be done

Gallstone
Gallbladder stone treatment
  • Gallbladder Stone Treatment

The standard Gallbladder Stone Operation is surgical removal of the Gallbladder. Unlike kidney stones in which only stones are removed in case of gallstones, the gallbladder is removed. The gallbladder has no major function in our body. Gallbladder which is being removed is already diseased one and dose not effect our digestion

  • Laparoscopic Cholecystectomy

Lap cholecystectomy is the most common abdominal surgery. It is daycare surgery in which surgery is done in the early morning and the patient can be discharged by the evening. From next day onwards patient can do all his daily normal activities

Dr. Amit Jain MCh Gastrointestinal Surgeon at Max Hospital Patparganj Delhi and Vaishali Ghaziabad is a best laparoscopic surgeon in Delhi for Gallstone surgery. He has been trained at GB Pant Hospital one of the best GI Surgery Institute in India. He has performed various complex GI Surgery in the last 15 years. He is fellow in Advance Laparoscopic Surgery

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Gallbladder Stone Complications: What Gallstones Can Do

Gallbladder stone disease is common.Ultrasound abdomen is the commonest investigation for any abdomen complaint. The result being the incidence of asymptomatic gallstones is also increasing. Incidence of Gallbladder stones is more in females. There are various theories about formation of gallbladder stones.

  • Gallbladder Stone ComplicationsGallbladder Stone Complications

It is said that in 90% of patients the first complaint of Gallstones is right upper abdomen pain. After the first episode the frequency of pain abdomen increases and so the complication rate. In 10% of patients, the first presentation can be one of the complications of Gallbladder Stone. The complications of gallbladder stone include Jaundice/Cholangitis/pancreatitis/Cancer Gallbladder/fistulous communication to nearby organs, when the stone in the gallbladder pass to common bile duct through cystic duct patient can have just jaundice if it simply obstruct the CBD lumen and prevent passage of bile from CBD to duodenum. This obstruction when leads to infection patient will have fever and it is called as cholangitis. Cholangitis is a serious condition and patient may develop septic shock and require urgent biliary drainage.

  • Biliary pancreatitis

It is another life threatening complication. Passage of stone lower down causes temporary blockage of pancreatic secretions and can cause biliary pancreatitis.

Long-standing inflammation anywhere in the body predispose to cancer so in case of Gallbladder Stone. Gallbladder stone is known risk factor for Gallbladder Cancer. Incidence of cancer is very minimal. This is not an indication for surgery in asymptomatic gallstone patients.

  • Treatment 

The standard treatment is Laparoscopic Cholecystectomy. Advantage of laparoscopy surgery is less pain and early discharge. It is day care surgery in which patient can be discharged on same day of surgery

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Dr. Amit jain is best Gastrosurgeon in Noida, Ghaziabad, Indrapuram, Delhi NCR India for Gallbladder Stone Surgery.

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Gallbladder Cancer Symptoms You Must Know

Gallbladder Cancer incidence is more in Northern part of India. It is important to know gallbladder cancer symptoms. If we know these symptoms we may consult to doctor early and have early diagnosis. Early diagnosis and treatment is key for long term survival rate in gallbladder cancer patients.

  • Gallbladder Cancer Symptoms

The most common Gallbladder cancer symptom is pain localized to right upper abdomen. Anorexia and weight loss are common symptoms as seen in other cancer. Gallbladder cancer patients can present with gastric outlet obstruction symptom that is vomiting. It occur when gallbladder cancer involve gastric antrum or pylorus or duodenum. When cancer involve hilum it can cause biliary obstruction leading to jaundice. This jaundice is called as surgical obstructive jaundice. Its feature are generally it is painless, dark colored urine and pale colored stools. Gallbladder cancer can involve hepatic flexure of colon. When it involve colon patient present with feature of large bowel obstruction like abdomen distension, non-passage of flatus and motion. Metastatic gallbladder cancer present with abdomen distension in the form of ascites.

  • Gallbladder Cancer SymptomsGallbladder Cancer Diagnosis

When patient present with gallbladder cancer symptoms first line of investigation is USG whole abdomen. It will detect any mass in the gallbladder or any focal thickening. CECT abdomen is done for local tumor invasion and distant metastases.

The standard treatment is surgery if tumor is resectable. Surgery done is radical cholecystectomy in which Gallbladder is removed along with Liver wedge and lyphadenectomy is done.

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Consult Dr. Amit Jain Best Oncologist in Delhi Noida for any query regarding Gallbladder Cancer. It is important to remember that Gallbladder Cancer prognosis is good if detected early.Do not ignore above mentioned symptoms. Make an appointment for Dr Amit Jain at 7351088686 to know about Gallbladder Cancer Symptoms and Gallbladder Cancer Treatment.

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